Acupunture Mechanisms Revealed

Research on mice by da Silva et al has revealed new mechanisms underpinning the workings of acupuncture. They injected carrageenan into the calf muscles of mice. This created an inflammatory response with associated pain and swelling. Manual acupuncture of Spleen 6 (an acupuncture point in the lower leg) reduced pain, heat and swelling of the muscle. Repeated acupuncture of Spleen 6 produced a phenotypic change from pro-inflammatory cells (M1 macrophages) to anti-inflammatory cells (M2 macrophages) with an associated increase in interleukin-10 concentrations in muscle which led to reduced pain and inflammation.