High Uric Acid: Beyond Gout
Did you know that high uric acid can create very different clinical presentations: the classic exquisite pain in a single joint or generalised muscle soreness?
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Excess Dietary Salt Leads To Cognitive Impairment
Faraco et al. recently discovered mechanisms by which salt-rich diets can lead to cognitive dysfunction in mice. An increase in dietary salt led to a deficiency of nitric oxide in cerebral blood vessels. As nitric oxide is a vasodilator, the reduced levels resulted in decreased cerebral blood flow. In addition, nitric oxide deficiency causes the…
Tendinopathy: The New Science of Pain and Repair
This summary is based on the Nature Reviews Disease Primers article “Tendinopathy” by Neal L. Millar et al. (published in 2021). It outlines the current scientific understanding of the condition’s pathology, diagnosis, and management. Overview Tendinopathy is a complex, multifaceted clinical syndrome characterised by persistent pain, localised swelling, and impaired performance. It is a spectrum of changes that occur…
Chronic Pain And Emotion
Professor Apkarian has studied chronic pain for over 20 years. In a recent study looking into people with recent back pain, he was able to predict with 85% accuracy those that would go on to develop chronic back pain! How? By noticing an increased level of cross-talk between two specific parts of the brain…suggesting that…
Meal Times Crucial For Weight Loss
A few months ago Lopez-Minguez et al. reviewed studies looking at the effect of meal times on obesity and metabolic risk. Their findings are summed up in the following points: skipping breakfast is linked to obesity eating a large breakfast (within 2hrs of waking) decreases the probability of being obese by 50% a late lunch…
Manage Longstanding Low Back Pain by Spending Time in Nature
Study Overview The article “Being away from everything”: Exploring the importance of access to nature for individuals living with chronic low back pain, published in the Journal of Pain, investigates how nature can aid in managing chronic low back pain (cLBP). It involved ten semi-structured interviews with people averaging 50.1 years old and living with…
Living Near Green Spaces Improves Health
Today BBC News published an interesting article on work done by Mathew White from the European Centre for Environment and Human Health at the University of Exeter. He recently conducted a study looking into the benefits of green spaces on health and well-being. The findings of a previous study showed that people living in greener urban…