High Uric Acid: Beyond Gout
Did you know that high uric acid can create very different clinical presentations: the classic exquisite pain in a single joint or generalised muscle soreness?
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Cholesterol and Musculoskeletal Health
High cholesterol is a well-established risk factor for cardiovascular diseases, such as coronary artery disease and stroke. It is primarily associated with the development of atherosclerosis, characterised by the accumulation of cholesterol-laden plaques in arterial walls (Libby et al., 2019; Virmani et al., 2020). However, recent studies have uncovered a relationship between cholesterol metabolism and…
The Brain Can Learn To Decrease Pain
New research led by Raymonde Scheuren from the University of Luxembourg has brought some new insights into the world of pain. It’s generally known that a pain present in one part of the body can be attenuated by painfully stimulating a different part of the body. This is known as diffuse noxious inhibitory control (DNIC) and…
Stress Affects Brain Function and Structure
Echouffo-Tcheugui et al., from Harvard Medical School, recently published a paper studying the effects of stress on brain function and structure in over 2000 middle-aged participants from the Framingham Heart Study. They measured early morning serum cortisol as an indicator of stress levels. They found that “higher cortisol was associated with worse memory and visual perception, as well as…
Revolutionising Cellular Regeneration and Longevity With AI
The article “Accelerating life sciences research,” published by OpenAI on 22 August 2025, outlines a significant collaboration between OpenAI and Retro Biosciences aimed at advancing life sciences research through the application of artificial intelligence. The partnership has resulted in the development of GPT-4b micro, a specialised AI model derived from a scaled-down version of OpenAI’s…
Shift Work May Cause Obesity And Diabetes
An article in today’s BBC News Health discusses recent research published in Science Translational Medicine. Dr Orfeu Buxton et al. have shown that “prolonged sleep restriction with concurrent circadian disruption alters metabolism and could increase the risk of obesity and diabetes”. This has implications to people performing shift work.
Sweeteners Increase Cardiovascular Risk
Earlier this year I wrote about the results of a large study evidencing the association between artificial sweeteners and cancer risk. Debras et al. used the same cohort (Nutrient-Sante) of over 100,000 participants. But this time, they looked at the association between artificial sweeteners and cardiovascular disease risk. The study was published in The British…