Sleep Deprivation Can Negatively Affect Cholesterol Levels And Inflammation
- At April 25, 2016
- By Healing In Motion
- In Research
0
Vilma Aho et al from the University of Helsinki conducted 2 studies looking into the effects of sleep deprivation. The first study was experimental and consisted of partial sleep restriction to a small group of subjects. The second was an epidemiological study with over 2700 individuals. Blood samples were analysed in both cases.
The analyses revealed decreased circulating High Density Lipoproteins (HDL cholesterol), otherwise known as ‘good cholesterol’, and elevated inflammatory markers. Sleep loss decreased the expression of genes encoding cholesterol transporters and increased expression in pathways involved in inflammatory responses. The findings help to explain why sleep deprivation is a risk factor for cardiometabolic disease.
Why Is Calcific Tendinitis So Painful?
- At April 18, 2016
- By Healing In Motion
- In Research
- 0
There are a couple of shoulder conditions that can be extremely painful. One is adhesive capsulitis, better known as frozen shoulder, and the other is calcific tendinitis. Calcific tendinitis is characterised by the formation of calcium deposits in the rotator cuff tendons of the shoulder. A few months ago Hackett et al from the University of New South Wales published the results of a study that could explain why calcific tendinitis is so painful. Their findings are published in The Journal of Bone & Joint Surgery.
They concluded that there was “a significant increase in neovascularization and neoinnervation in calcific tendinitis lesions of the shoulder along with an eightfold increase in mast cells and macrophages. The findings are consistent with the hypothesis that, in calcific tendinitis, the calcific material is inducing a vigorous inflammatory response within the tendon with formation of new blood vessels and nerves”.
