Bright Light Effective for Depression

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The use of bright light therapy to treat seasonal affective disorder (SAD) is well documented and evidence based but I had never heard of using light therapy to treat nonseasonal major depressive disorder (MDD). Raymond Lam et al, from the Department of Psychiatry at the University of British Columbia, designed an elegant study comparing the effects of light therapy, drug treatment (Fluoxetine), combination therapy (light plus drug) and sham-placebo in adults with nonseasonal depression. Their study was published this month in JAMA Psychiatry.

Treatments were given daily for 8 weeks (the light therapy consisted of a 30 min early morning exposure to a 10,000-lux fluorescent white light box) and depression ratings were taken at baseline and at the 8-week end point. Interestingly, the drug antidepressant did not perform any better than the placebo. Both the light therapy and combination therapy showed significant clinical benefit. The combination therapy had the most consistent effects.

The news that light therapy is effective for both SAD and nonseasonal depression means that there is now a new way of treating depression that has few if any side effects. For more stubborn cases a combination of light and drugs can be used or maybe even a combination of light and cognitive behavioural therapy (CBT).

Tai Chi And CBT Decrease Inflammation

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Poor sleep has been linked to increased inflammation. Inflammation is known to cause or exacerbate musculoskeletal disorders as well as more serious diseases such as heart disease, stroke and cancer. Irwin and his colleagues conducted a randomised controlled trial looking into the effects of cognitive behavioural therapy (CBT) and Tai Chi on the inflammatory markers of subjects with insomnia. The participants were offered 2 hour weekly sessions for 4 months.

CBT was found to reduce systemic inflammation whereas Tai Chi reduced cellular inflammatory responses. Both interventions reduced the expression of genes encoding proinflammatory mediators.