The Miracle Cure

Scarlett McNally, a Consultant Orthopaedic surgeon, and her colleagues have spent 2 years analysing more than 200 separate pieces of research. The effect that regular exercise could have on our health is amazing. Exercise could:

• prevent type 2 diabetes
• reduce the risk of getting breast cancer by 25%
• decrease the risk of bowel cancer by 45%
• reduce the risk of having a stroke by 30%
• reduce the risk of developing dementia by 30%
• cut the risk of developing heart disease by over 40%
• as well as improvements to mental health

Exercise doesn’t have to be vigorous but it should be regular. Simply start by increasing your physical activity in whatever way you can: walk more, take the stairs, do some gardening, ride a bike…the possibilities are endless!

The 5 Habits of Highly Healthy People

Since 1979 Professor Peter Elwood and his team of researchers from Cardiff University School of Medicine have tracked the lifestyle habits of 2500 men aged 45-59 (at the start of the study). They found that men that followed 5 habits had 70% less chance of developing diabetes, 60% reduced incidents of heart attacks and strokes, 40% fewer cancers, and a reduction of 60% in cases of dementia. Incidentally, less than 1% of the study group followed all 5 habits! These 5 habits have the potential to reduce illness and chronic disease and so promote longevity…what are they?

The 5 habits of highly healthy people are:

• regular exercise
• no smoking
• a healthy bodyweight
• a healthy diet
• a low alcohol intake

Not rocket science by any means…and definitely within everyone’s grasp!

Relaxation For Health And Well-Being

The word ‘stress’ has become ubiquitous, but what exactly does it mean? It’s probably in the 1920s that it was first used in its present context. Walter Cannon used it to describe the process where external factors disturbed the body’s natural equilibrium. Around the same time, Hans Selye described stress as the non-specific response of the body to any demand placed upon it. Still confused?

Let’s put things a little more clearly. To ensure our survival we must either be in ‘protection mode’ or in ‘growth mode’. Protection mode ensures our short-term survival i.e. running away from or slaying a sabre-toothed tiger, moving out of the way of an oncoming car, etc. Growth mode ensures our long-term survival i.e. taking in nutrients by eating and digesting a meal, recharging our batteries by sleeping, wound-healing, having sex and reproducing, etc. Protection mode is more commonly known as ‘fight-or-flight’ and growth mode as ‘rest-and-digest’. They are like two sides of the same coin…it’s either one or the other…we’re either in ‘fight-or-flight’ or we’re in ‘rest-and-digest’. You may be more familiar with ‘fight-or-flight’ or the stress response as it’s also known.

The stress response kicks in as soon as we sense a threat. Things start off in the amygdala deep inside our brains. Other areas of the brain (hypothalamus, pituitary gland) also become involved as does the sympathetic nervous system. The adrenal glands then release adrenaline and cortisol. The aim is to quickly prepare the body for vigorous muscle activity by releasing fats and glucose into the blood stream, increasing the heart rate and breathing rate, dilating blood vessels in muscles, increasing blood pressure and increasing muscle tension. All this helps get us immediately primed for action without having to go through any mental preparation or physical warm-up! It sounds too good to be true and it’s helped us survive and thrive through time. Fortunately nowadays, we don’t often face the type of physical emergency the fight-or-flight system was designed for…but our brains still perceive lots of threats out there…traffic jams, time pressures, bad bosses, financial worries, difficult partners, noisy kids, not to mention 24/7 connectivity, contactability and accountability with the advent of new technology! All this ends up firing off our stress response in a completely different context than that for which it was designed. Rather than a sporadic short blast, it’s now more of a constant slow simmer…without the physical activity required to reset the system. Almost like preparing for a battle that never arrives…revving a car that never goes anywhere.

This ongoing low-level stress response has negative consequences. According to the Mayo Clinic, if left unchecked, “stress can contribute to health problems such as high blood pressure, heart disease, obesity and diabetes”. They cite the following common effects of stress:

What’s the solution? The key is to find a way of getting ourselves back into ‘rest-and-digest’ mode. In 1968 Herbert Benson, a cardiologist from Harvard Medical School, fortuitously stumbled across something whilst studying blood pressure. He had been approached by a group of transcendental meditators claiming they could lower their blood pressures through the use of their minds! Initially sceptical and reluctant to study them, he eventually succumbed and discovered what he called the ‘relaxation response’. Benson described the relaxation response as the opposite of the ‘fight-or-flight’ or stress response, it’s essentially the ‘rest-and-digest’ mode mentioned earlier. He characterised it by:

• Decreased metabolism, heart rate, blood pressure and rate of breathing
• A decrease or calming in brain activity
• An increase in attention and decision-making functions of the brain
• Changes in gene activity that are the opposite of those associated with stress

Research has found that the relaxation response can be effective in treating the following complaints:

Additionally, research shows that mind-body techniques can also be effective in treating the following:

In summary, any symptom or disease caused or exacerbated by stress can be helped by relaxation. Happily, there are lots of ways to evoke the relaxation response such as relaxation techniques (progressive relaxation, passive muscular relaxation, Mitchell method, breathing exercises, etc.), meditation, prayer, yoga, tai chi, exercise, cognitive behavioural therapy and hypnosis.

Hypnosis is a personal favourite of mine. It can combine the immediate relaxing effects of relaxation techniques with a change in thinking, mood and behaviour such as can be obtained using CBT. Better still, because it uses the power of the unconscious mind, these changes take place effortlessly…as if by magic!

Give it a go (click on the icon to go directly to the shop)!

Relax and enjoy better physical health and mental well-being.

Living Near Green Spaces Improves Health

Today BBC News published an interesting article on work done by Mathew White from the European Centre for Environment and Human Health at the University of Exeter. He recently conducted a study looking into the benefits of green spaces on health and well-being. The findings of a previous study showed that people living in greener urban areas were showing fewer signs of depression or anxiety.

Various things such as job promotions, pay rises, winning the lottery, etc. can make people happier but the effects last for only 6 months to a year. These things don’t lead to long-term happiness. Dr White examined data from the British Household Panel Survey (about 40,000 households). What he found was that living in an area with green spaces, like parks, has a lasting beneficial effect on mental health (happiness, depression, anxiety).

As the mind and body are entwined, I’m sure there must also be physical benefits to living near green spaces.

Meaning And Purpose Improve Health

Steven Cole et al. from UCLA have recently shown that having a deep sense of purpose and meaning in life can lead to positive genetic changes such as lowering the levels of inflammatory gene expression and strengthening the expression of antiviral and antibody genes. Theoretically, this could mean that those with a strong sense of purpose and meaning have a more efficient immune system and are less susceptible to inflammatory diseases.

Parallels can be drawn with Viktor Frankl’s influential book ‘Man’s Search For Meaning‘. In it, he relates his experiences of life in concentration camps during WWII. He believed that finding a meaning to life was crucial to survival in those terrible circumstances. After the war, he continued his work as a psychiatrist with logotherapy (a form of existential analysis) and became convinced that happiness was to be attained by finding meaning and purpose in life.

Healthy Water For A Longer Life

Last year I wrote an article on hydration, the signs of dehydration and how much water we need to drink each day. We now know how much water to drink but what water is best? I found a great little book called “Healthy Water for a Longer Life” by Martin Fox. It reviews an extensive body of research carried out on the effects of the quality of water on health. Although it was published in 1986, I don’t think there exists a more comprehensive book on the subject. What follows is a summary of the main points.

High levels of water hardness and total dissolved solids have been linked with decreased cardiovascular disease. Hard water is water that has high levels of calcium carbonate or magnesium carbonate. In areas with hard water, you’ll notice your kettle fur up pretty quickly and in areas with soft water you’ll find it harder to wash off soap when showering. British studies have suggested hardness of at least 170 mg/l for health benefits. In the north of England, the neighbouring towns of Scunthorpe and Grimsby drank the same water for years. Scunthorpe then softened its water from 448 mg/l to 100 mg/l and Grimsby continued with the same water as before. This led to a striking increase in cardiovascular disease in the town that softened its water!

No correlation between sodium levels in water and hypertension or mortality has been found. This is probably because only 10% of our sodium intake comes from water and the rest comes from food. So avoiding processed foods and not salting our food has a bigger impact on our health.

Increased water hardness, increased total dissolved solids, increased pH and increased silica (SiO2) are each linked to decreased risks of cancer.

Fluoride is thought to prevent caries but its use is controversial due to the risk of cancer, genetic damage and birth defects. Water fluoridation has been abolished in most of Europe but continues in some parts of North America. High levels of water hardness and total dissolved solids can negate the deleterious effects of naturally occurring fluoride. Studies of dental caries in primitive groups have found that a healthy unrefined diet leads to healthy teeth.

Chlorination of water has saved countless lives by killing harmful bacteria but it has also led to an increase in atherosclerosis, heart disease and cancer. This is thought to be caused by a release of free radicals.

Animal experiments have shown that hard water provides protection from potentially harmful agents such as cadmium, lead, chlorine and dietary fat. An interesting calcium-chlorine relationship has been found. Pigeons were fed a diet that contained only 80% of the recommended daily allowance (RDA) of calcium. Half the birds were given unchlorinated water and the rest drank water that contained 10 mg/l of chlorine. Three months later the pigeons that drank chlorinated water had blood cholesterol levels that were 50% higher than the group that drank unchlorinated water. Further tests showed that pigeons given a normal diet show no differences in cholesterol levels between those that drink chlorinated water and those that don’t. When 10% lard is added to a calcium deficient diet, pigeons that drink unchlorinated water only have a minor increase in cholesterol but those that drink chlorinated water have cholesterol levels that increase about 3 fold!

Some people claim that demineralised water is better for health but there is no rationale or scientific study to support its benefits. In fact, the reverse is true…soft water is hazardous to health. Minerals with beneficial effects are: silica, magnesium, chromium, lithium, vanadium, calcium and zinc. Interestingly, mineral absorption is greater from drinking water than from food and protein enhances the absorption. If essential elements are present in water, there is less absorption of non-essential (toxic) elements.

Finally, which water is best? It has to have a presence of essential minerals and an absence of harmful minerals and compounds. Tap water may be suitable but one would have to verify its composition with the water company…a water filtration system may be required to remove harmful compounds (inorganic and organic)…the quality of filtration systems varies widely…and one has to be careful to avoid a build up of bacteria within the filtration unit…

By far the easiest option is to select bottled mineral water that satisfies the following criteria:

• approximately 300 mg/l of total dissolved solids
• around 170 mg/l hardness (calcium carbonate)
• an alkaline pH (over 7)

Cheers!

Shift Work May Cause Obesity And Diabetes

An article in today’s BBC News Health discusses recent research published in Science Translational Medicine. Dr Orfeu Buxton et al. have shown that “prolonged sleep restriction with concurrent circadian disruption alters metabolism and could increase the risk of obesity and diabetes”. This has implications to people performing shift work.

Have Some More Chocolate!

Easter is upon us and as usual, we’re about to indulge in fistfuls of chocolate….so I thought I’d remove the guilt by telling you about some of the potential benefits! Extensive research has shown that the cocoa in chocolate can help: improve arterial blood flow and decrease blood pressure, improve glucose and fat metabolism, and improve vascular and platelet function. A 50% decrease in mortality, mostly due to decreased myocardial infarction, has been seen. The mechanisms underlying the effects are thought to be due to the activation of nitric oxide as well as antioxidant and anti-inflammatory effects.

What type of chocolate is best and how much should we have? It’s been recommended that we eat up to 25g/day of flavanol rich dark chocolate (85% cocoa content) for cardiovascular prevention. The belief is that, at this dose, the effects on weight gain and Cadium intake are minimal.

Enjoy…Happy Easter!

Sitting And Mortality

A few days ago the Archives of Internal Medicine published the timely results of the effects of sitting on mortality rates. van der Ploeg and her colleagues followed over 220,000 Australians over a 3 year period. The subjects were 45 years or older and sadly 5405 people passed away during the course of the study. The researchers found that mortality risks increased with daily sitting time. Compared to people who sat less than 4 hours a day, those that sat for 4-8 hrs had a 2% increased risk of mortality. Whereas those that sat for 8-11 hrs a day increased their risk by 15% and the subjects that sat for over 11 hrs increased their risk of death by a whopping 40%!

Fascinatingly, their results revealed that prolonged sitting was a risk factor for mortality independent of physical activity. Probably because “time spent doing moderate or vigorous exercise and time being totally sedentary may affect long-term disease risks separately.”

Don’t be too depressed about it…we all have to go at some stage…but if you prefer to leave later rather than sooner, have a look at my previous post ‘I Wouldn’t Sit For That (Part 2)‘ for some helpful tips!

The Obesity Paradox

According to research, obesity is to a certain extent genetically determined. The pandemic now affects a billion people and has gradually grown over the last 150 years. Interestingly, our genes have not changed over that period. So how could obesity, which is genetically determined, have appeared over a time when our genes have remained unchanged? What has changed?

Well, over 150 years ago 90% of the population lived an agricultural lifestyle. They walked to work, performed active physical work, walked home after work. Water had to be carried and clothes washed by hand. Our lifestyles were much more similar to those of our distant ancestors in that, we stood and walked for most of the day.

With the advent of industrialisation and urbanisation 50% of the world’s population moved to the cities. This figure is even higher in developed countries. Factory work became prevalent and chair-based work replaced standing just like machine operation replaced tool use. The biggest change has taken place over the last 25 years…over half the population in the developed world now sits in front of a computer for 8 hours a day. As a result of these changes, our occupational energy expenditure could have decreased by as much as 1200 kcal/day.

At home most of us have a personal computer and we spend a few more hours banking, shopping, browsing and even socialising (Facebook, Twitter, MySpace, etc)! Oh, and if we’re not sitting in front of the computer it’s probably the television…another brilliant invention that appeared in the last century. Sales of labour-saving devices like washing machines, dishwashers and cars track obesity rates and it’s estimated that mechanisation saves  around 111 kcal/day.

Obviously food has become more available (in industrialised countries) and one could assume that our intake has increased. Surprisingly, in the UK since the 1980s, energy intake seems to have decreased whereas obesity rates have doubled! Statistics in the US show that intake hasn’t changed but obesity has skyrocketed…

Here’s a quick thermodynamics refresher…when energy is added to a system it’s either used to perform work or stored…if the energy intake is greater than the energy expenditure, the excess is stored as fat…if the energy imbalance continues over several months or years it leads to obesity. It’s becoming clear that it’s the decrease in our activity that has lead to the weight gain.

How come we haven’t all been affected by this? This is where the genetics plays it’s part. Those of us that are genetically programmed to conserve energy have blossomed in this new modern environment, the rest have found other ways to replace their need for movement: walking or cycling to work, pacing about at work, getting involved in DIY at home, going to the gym or taking part in sports or active hobbies. Crucial research shows that lean sedentary people stand and walk for about 2.5 hrs/day more than obese people. If obese individuals were to stand and walk 2.5 hrs more each day it would equate to an expenditure of 350 kcal/day which is exactly the figure that was identified in a different study to determine the amount of exercise that obese people had to undertake to help weight loss.

Why should we care about obesity? Perhaps because it’s been linked to type 2 diabetes, hypertension, stroke, arthritis, sleep apnea and cancer…maybe because obesity related medical expenses are out of control and  in the US they reached $75 billion in 2003!

What’s the best way to lose weight? Is it through exercise or non-exercise activity? Or both? According to Dr Levine, the majority of people who exercise for just under 2 hours a week expend an average of about 100 kcal/day. This is a drop in the ocean compared to what it’s possible to achieve by increasing non-exercise activity. Granted, we can’t all change our jobs and become lumberjacks or tree surgeons but we can become more active both at work and at home. Our muscles are almost completely silent when seated and as a consequence, our energy expenditure is negligible…our expenditure goes up 15% when standing and doubles when ambling…purposeful walking can double or triple it! So, spending less time sitting seems to be the key to burning up more calories.

Prolonged sitting time has been linked to metabolic syndrome, type 2 diabetes, obesity and cardiovascular disease. This is thought to be the result of poor fat metabolism due to the decreased production of lipoprotein lipase in muscles when seated. Non-exercise activity reverses this process.

It appears our technological innovations have had insidious effects on our health. The antidote lies in freeing ourselves from the chair…can we afford to wait for governments and corporations to reengineer our workplaces? Probably not…we must all take responsibility for our health and those among us that have a predisposition towards energy conservation need to take active measures by simply standing and walking about more often and for longer periods during the day.

Most of the information in this post is inspired from the work of Dr James Levine, Professor in the Department of Endocrinology at the Mayo Clinic in Rochester MN